Our new Clear+ tissue clearing procedure is the only system that delipidates samples without transform in morphology and with minimum effect on structural integrity.
Megatome is actually a vibrating microtome intended to section a broad choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform floor profile, along with negligible tissue harm and data loss.
Antibodies may well acquire weeks to diffuse as a result of only a few millimeters of tissue, having a steep labeling gradient from surface area to Main.
Megatome is made for precision: the blade vibrates at an increased frequency and larger amplitude assortment than other microtomes, and incorporates a exclusive deflection Handle mechanism.
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Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them entirely transparent. This allows mild penetration megatomi.com to the sample and makes sure the acquisition of large-resolution, in-aim picture facts.
Megatome is usually a novel microtome which allows for prime-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with small tissue problems and data reduction.
It’s time and energy to update your microtome to Megatome. With correct large-frequency slicing for an unmatched variety of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous programs.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition pace during intact tissue volumes, although its modular layout helps you to enhance and personalize personal components.
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SHIELD avoids the variability of hydrogel embedding and the knowledge loss from PFA preservation, protecting specimens for several rounds of processing.
Leverage the Apparent+ tissue clearing process, along with eFLASH and patented stochastic electrotransport technologies, to fast distinct and label entire organs. Important highlights and functions contain:
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